Games like Master of Orion 2. 23 Similar Games.

1. Master of Orion. (1993) 
2. Space Empires 4. (2000)
3. Galactic Civilizations. (2003) 
4. Endless Space. (2012)
5. Ascendancy. (1995)
6. Distant Worlds. (2010)
7. Star Wars: Rebellion. (1998)
8. Sins of a Solar Empire. (2008) 
9. Nexus: The Jupiter Incident. (2004)  
10. Armada 2526. (2009)
11. Haegemonia: Legions of Iron. (2002)
12. Sword of the Stars. (2006)
13. Lost Empire. (2007)
14. Star Wars: Empire at War. (2007) 
15. Endless Space. (2012)
16. Imperium Galactica 2. (2000)
17. Star Trek: Birth of the Federation. (1999)
18. Pax Imperia: Eminent Domain. (1997)
19. Civilization 4: Dune Wars. (2009)
20. Civilization 4: Planetfall. (2006) 
21. Civilization: Beyond Earth. (2014)
22. Sid Meier's Alpha Centauri. (1999) 
23. Endless Legend. (2014)